Browse WD40 genes
A total of 89 WD40 domain-containing genes in serotype A Cryptococcus neoformans var. grubii are archived in the database, based on domain annotation.
Browse genesCryptococcus neoformans WD40 Phenome Database
Welcome to the WD40 Phenome
knowledgebase
Browse WD40 domain-containing genes and explore functional phenotypic data from gene knockout and CTR4 conditional knockdown experiments.
Domain annotation
Phenotype profiling
Database Summary
C. neoformans
# Total WD40 Genes
· · · 89
; Knockout Phenotype
· · · 53
; CTR4 Conditional Knockdown Phenotype
· · · 36
Phenotype database
Functional phenotypic traits under multiple growth conditions are available for each WD40 gene, obtained from RNA-seq analyses under gene knockout or CTR4 conditional knockdown experiments.
Functional annotation
Each entry provides detailed annotations such as Pfam and KEGG orthology. Integrated JBrowse and ProteinPlus links enable contextual visualization of genomic loci, expression profiles, and protein interaction potential.
Structural insights
Explore AlphaFold-predicted 3D structures with WD40 domains highlighted. WD40 domains are annotated using HMMsearch against the Pfam database (PF00400.38; canonical WD40).
About the resource
From annotation to phenotype.
This database integrates WD40 domain annotation and phenotype data for Cryptococcus neoformans. Each entry provides multiple links to gene details and associated experimental results.
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