Detailed Locus Information for CNAG_07453
| Species | Cryptococcus neoformans var. grubii H99 | ||||
|---|---|---|---|---|---|
| Gene Annotation | hypothetical protein | ||||
| Gene Symbol | TEX1 | ||||
| NCBI Protein ID | XP_012049139.1 | ||||
| UniProt ID | J9VLW3 | ||||
| KEGG Linkout | N/A | ||||
| Genome Browser | JBrowse link goes here. Sequence information also available from JBrowse. | ||||
| Functional Annotation | |||||
| Amino Acid Sequence | MTDGSEAYNIDAFPNADFSARELPRPSFSRTQDVRGLVKHVRTVAWSSDGKKAATGGEYKEIQVWDESLDSKTTTPLPSASKPSPHNHHVSSIAWSPVDPNVLVSADKTFSVGSVIAVWDVTSPSAPVATFKTPGDVINLAWHPSGQHFAAVYPVKSRDLVDFFRLLTNESGEPKWEKREDITLGGLSHGIGSEEINSLRFINSGRLVCAVSNDGSVSAWIYPVESVRVDLADEQMEPEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEEQEQEQEKRQGQEQEEKEPEVVTEGKEDGVITKEMATEKEDEVVTEEKEDKEGKGNKEEGQNKEDKESREEEQIKKDKQDAGDGPATPELPATETLAEEPIGDVKPAESNGDVEMTETDNAEAKANEESKEDEALETNKPESQDVDMVDAAQTHTQPSSVQPSRQPTPPPAKASPKPRAQPLKRYRHVVCYAASLLSLAYDPRGRYFVVGGQDALLSLFDTKEWICERSFDVCSAAIRHTAFSYDGEFVAIGGDDLFIAIVSVYTGQTVAKIPIPAAVNALSWNPRKNSLAYCHQGKGGVPLWHIVHQE | ||||
| AlphaFold Structure with WD40 domains |
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Mutant Construction Design (Knockout)
| Gene Name | Primer Name | Sequence |
|---|---|---|
| TEX1 | B14171 CNAG_07453 5’ flanking region primer L1 | TGCAACAAATGGACGTTAGG |
| B14172 CNAG_07453 5’ flanking region primer L2 | TCACTGGCCGTCGTTTTACGCCGCTTTCTTACCATCAGA | |
| B14173 CNAG_07453 3’ flanking region primer R1 | CATGGTCATAGCTGTTTCCTGCTATACCGGCCAAACTGTCG | |
| B14174 CNAG_07453 3’ flanking region primer R2 | CTTGCCGGAATCATCAATCT | |
| B14175 CNAG_07453 diagnostic screening primer SO, pairing with B79 | GGTTGGGAATTTCCAGCTTT | |
| B14176 CNAG_07453 Southern blot probe primer PO | CCCATTTTGGTTCACCACTC | |
| B15022 CNAG_07453 diagnostic screening primer SO2, paring with JOHE12579 | GCAATTGGAAAGGAGGATGA | |
| B15023 CNAG_07453 Internal_LP | GGGACGTCACCTGTGAGTTT | |
| B15024 CNAG_07453 Internal_RP | ACCTCAGGCTCCTTCTCCTC | |
| B5508 NAT#184 STM primer | ATATATGGCTCGAGCTAGATAGAG | |
| B5532 STM common primer | GCATGCCCTGCCCCTAAGAATTCG |
Phenotype Assays
| Growth | |
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| Mating Data | |
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| Virulence Factor Production | |
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Capsule
Urease
Melanin
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| Stress Response and Adaptation | |
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Osmotic Stress
Oxidative Stress
Heavy Metal Stress
Endoplasmic Reticulum Stress
Cell Wall Stress
Genotoxic Stress
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| Antifungal Drug Susceptibility | |
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| Organ Infectivity Data by the Signature-tag Mutagenesis-based Murine Host Model | |
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